The 2025/2026 Premier League season has just kicked off, and it promises to be another thrilling campaign. With Liverpool defending their title, the competition is expected to be fierce, and the fixture list is full of matches that could define the season. Here is a breakdown of the key matches and weeks to watch out for.
The Opening Weekend
The new season began on Friday, August 15, with reigning champions Liverpool hosting AFC Bournemouth at Anfield. The opening weekend is packed with intriguing clashes, including a “Big Six” showdown.
- Liverpool vs. AFC Bournemouth (August 15): The champions start their title defense against a team they have historically dominated.
- Aston Villa vs. Newcastle United (August 16): A rematch of a key fixture from last season’s battle for European places.
- Wolverhampton Wanderers vs. Manchester City (August 16): A tough away opener for Pep Guardiola’s side.
- Manchester United vs. Arsenal (August 17): A massive early-season test for both clubs, who will be hoping for a strong start to their respective campaigns.
- Leeds United vs. Everton (August 18): Leeds’ return to the Premier League is a big story, and they’ll be looking to make a statement in front of their home crowd.
Key Matchweeks to Watch
While every match is important, some periods in the season are particularly crucial due to the number of high-stakes encounters. Here are some of the weeks that could have a significant impact on the title race and the battle for European qualification.
- Matchweek 3 (August 30-31): The title race could get its first six-pointer very early on as Liverpool hosts Arsenal.
- Matchweek 4 (September 13-14): We get the first Manchester derby of the season as Manchester City hosts Manchester United. This is an early test for both sides’ ambitions.
- Matchweek 5 (September 20-21): A bumper weekend of big games. Manchester United hosts Chelsea, while Arsenal and Manchester City face each other. This is a brutal stretch for both Manchester clubs, as they play three of the “Big Six” in the first five rounds. Also, the first Merseyside derby of the season takes place as Liverpool hosts Everton.
- Matchweek 7 (October 4): A full slate of important matches, with Chelsea hosting Liverpool and Brentford taking on Manchester City.
- Matchweek 8 (October 18): The classic rivalry between Liverpool and Manchester United will be renewed at Anfield. This is a fixture that always has a significant impact on the league table and the title race.
- The Christmas Period: The festive period is notoriously challenging, with a condensed schedule of games. Navigating this period successfully can be a huge factor in a team’s title aspirations. There will be no fixture on Christmas Eve, but the traditional Boxing Day matches will be played.
- The Run-in (April and May): As the season draws to a close, every point becomes vital. The final few matchweeks will feature clubs fighting for the title, European places, and against relegation. The last match of the season, on Sunday, May 24, will see all ten games kick off simultaneously, as is tradition.
The 2025/2026 Premier League season is poised for a thrilling nine months of football. The early-season fixtures will set the tone, but it’s the ability to navigate the crucial periods and win the defining matches that will ultimately determine who lifts the trophy.

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